2ALU
Detection of new binding site in the C-terminal lobe of lactoferrin:Crystal structure of the complex formed between bovine lactoferrin and a tetrasaccharide at 2.1A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Lactotransferrin | polymer | 348 | 38027.0 | 1 | UniProt (P24627) Pfam (PF00405) In PDB | Bos taurus (cattle) | |
2 | B | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
3 | C | alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G53778HF) | |||
4 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 830.8 | 1 | In PDB GlyTouCan (G12488UT) | |||
5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
6 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
7 | A | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
8 | A | CARBONATE ION | non-polymer | 60.0 | 1 | Chemie (CO3) | |||
9 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
10 | water | water | 18.0 | 281 | Chemie (HOH) |
Sequence modifications
A: 342 - 689 (UniProt: P24627)
PDB | External Database | Details |
---|---|---|
Lys 565 | Asn 584 | see sequence details |
Glu 608 | Lys 627 | see sequence details |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 38027.0 | |
Branched | Number of molecules | 3 |
Total formula weight | 2490.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 563.9 | |
All* | Total formula weight | 41081.2 |