2ALF
crystal structure of human CypA mutant K131A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidyl-prolyl cis-trans isomerase A | polymer | 164 | 17847.3 | 1 | UniProt (P62937) Pfam (PF00160) | Homo sapiens (human) | PPIase, Rotamase, Cyclophilin A, Cyclosporin A-binding protein |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | water | water | 18.0 | 245 | Chemie (HOH) |
Sequence modifications
A: 2 - 165 (UniProt: P62937)
| PDB | External Database | Details |
|---|---|---|
| Lys 120 | Glu 119 | conflict |
| Ala 131 | Lys 130 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17847.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 17871.6 |
