2AL5
Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor 2 | polymer | 263 | 29221.7 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2 |
| 2 | C, E (A, B) | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID | non-polymer | 217.2 | 2 | Chemie (FWD) | |||
| 3 | D (A) | 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE | non-polymer | 219.2 | 1 | Chemie (4MP) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 711 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 117 (UniProt: P19491)
A, B: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | SEE REMARK 999 |
| Thr 119 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58443.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 653.5 | |
| All* | Total formula weight | 59096.9 |
