2AHX
Crystal structure of ErbB4/HER4 extracellular domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Receptor tyrosine-protein kinase erbB-4 | polymer | 617 | 69030.9 | 2 | UniProt (Q15303) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) In PDB | Homo sapiens (human) | p180erbB4; Tyrosine kinase-type cell surface receptor HER4 |
| 2 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | B | YTTRIUM (III) ION | non-polymer | 88.9 | 1 | Chemie (YT3) | |||
| 5 | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 616 (UniProt: Q15303)
| PDB | External Database | Details |
|---|---|---|
| Arg 0 | - | cloning artifact |
| Asp 524 | Gly 549 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 138061.7 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 3916.4 | |
| All* | Total formula weight | 141978.1 |
