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2AFW

Crystal structure of human glutaminyl cyclase in complex with N-acetylhistamine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glutaminyl-peptide cyclotransferasepolymer32937557.42UniProt (Q16769)
Pfam (PF04389)
Homo sapiens (human)QC, Glutaminyl-tRNA cyclotransferase, Glutaminyl cyclase
2C, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, G
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
4E, H
(A, B)
N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDEnon-polymer153.22Chemie (AHN)
5I, J
(A, B)
waterwater18.0591Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight75114.8
Non-Polymers*Number of molecules6
Total formula weight629.3
All*Total formula weight75744.1
*Water molecules are not included.

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PDB entries from 2025-12-24

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