2ACS
AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ALDOSE REDUCTASE | polymer | 315 | 35767.1 | 1 | UniProt (P15121) Pfam (PF00248) In PDB | Homo sapiens (human) | |
| 2 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | A | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 4 | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35767.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 935.5 | |
| All* | Total formula weight | 36702.7 |
