2A9Z
Crystal structure of T. gondii adenosine kinase complexed with N6-dimethyladenosine and AMP-PCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | adenosine kinase | polymer | 383 | 40584.1 | 1 | UniProt (Q9TVW2) | Toxoplasma gondii | AK; Adenosine 5'-phosphotransferase |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 3 | C, D (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 4 | E, F (A) | 6N-DIMETHYLADENOSINE | non-polymer | 295.3 | 2 | Chemie (26A) PubChem (23793378) PubChem (44164301) PubChem (46874720) PubChem (51377241) PubChem (57200553) PubChem (72266) PubChem (348206) PubChem (10469765) PubChem (90084187) PubChem (440004) PubChem (688445) PubChem (124397351) PubChem (5343054) PubChem (6541395) PubChem (6614704) PubChem (7074915) PubChem (7074916) PubChem (7074917) PubChem (7074918) PubChem (13506501) PubChem (163284938) PubChem (174345725) | |||
| 5 | G (A) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) PubChem (46936826) PubChem (91532) PubChem (91885473) PubChem (4799) PubChem (157749842) PubChem (134943439) PubChem (157749839) | |||
| 6 | H (A) | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A: 1 - 363 (UniProt: Q9TVW2)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 270 | Gly 270 | engineered mutation |
| Phe 360 | Ser 360 | engineered mutation |
| Thr 361 | Leu 361 | engineered mutation |
| Ser 362 | Pro 362 | engineered mutation |
| Gly 363 | Cys 363 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40584.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1177.2 | |
| All* | Total formula weight | 41761.3 |
