2A75
Trypanosoma rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | sialidase | polymer | 652 | 71205.2 | 1 | UniProt (O44049) | Trypanosoma rangeli | |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid | non-polymer | 327.3 | 1 | Chemie (FSI) PubChem (23628524) PubChem (23628525) PubChem (150864) PubChem (448471) PubChem (58753593) PubChem (71065668) PubChem (72206646) PubChem (91532921) PubChem (9949281) PubChem (11450242) PubChem (14101566) PubChem (118479993) PubChem (129678999) PubChem (129715278) PubChem (134972939) PubChem (135016585) PubChem (155168392) PubChem (168356717) PubChem (168373736) | |||
| 4 | E (A) | water | water | 18.0 | 615 | Chemie (HOH) |
Sequence modifications
A: 1 - 638 (UniProt: O44049)
| PDB | External Database | Details |
|---|---|---|
| Met -13 | - | cloning artifact |
| Gly -12 | - | cloning artifact |
| Gly -11 | - | cloning artifact |
| Ser -10 | - | cloning artifact |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Gly -3 | - | cloning artifact |
| Met -2 | - | cloning artifact |
| Ala -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| Ile 50 | Thr 72 | SEE REMARK 999 |
| Ala 186 | Gly 208 | SEE REMARK 999 |
| Leu 372 | Phe 394 | SEE REMARK 999 |
| Val 606 | Ile 628 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 71205.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 519.4 | |
| All* | Total formula weight | 71724.6 |
