2A75
Trypanosoma rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | sialidase | polymer | 652 | 71205.2 | 1 | UniProt (O44049) Pfam (PF13859) Pfam (PF22925) | Trypanosoma rangeli | |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid | non-polymer | 327.3 | 1 | Chemie (FSI) | |||
| 4 | E (A) | water | water | 18.0 | 615 | Chemie (HOH) |
Sequence modifications
A: 1 - 638 (UniProt: O44049)
| PDB | External Database | Details |
|---|---|---|
| Met -13 | - | cloning artifact |
| Gly -12 | - | cloning artifact |
| Gly -11 | - | cloning artifact |
| Ser -10 | - | cloning artifact |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Gly -3 | - | cloning artifact |
| Met -2 | - | cloning artifact |
| Ala -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| Ile 50 | Thr 72 | SEE REMARK 999 |
| Ala 186 | Gly 208 | SEE REMARK 999 |
| Leu 372 | Phe 394 | SEE REMARK 999 |
| Val 606 | Ile 628 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 71205.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 519.4 | |
| All* | Total formula weight | 71724.6 |
