2A5G
Cholera toxin A1 subunit bound to ARF6(Q67L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosylation factor 6 | polymer | 175 | 20095.2 | 1 | UniProt (P62330) Pfam (PF00025) | Homo sapiens (human) | |
| 2 | B (B) | Cholera enterotoxin, A chain | polymer | 193 | 21710.8 | 1 | UniProt (P01555) Pfam (PF01375) | Vibrio cholerae | |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 5 | E (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 2 - 175 (UniProt: P62330)
B: 1 - 192 (UniProt: P01555)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Leu 67 | Gln 66 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | cloning artifact |
| Asp 110 | Glu 128 | engineered mutation |
| Asp 112 | Glu 130 | engineered mutation |
| Ser 187 | Cys 205 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41806.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 42376.4 |
