2A5G
Cholera toxin A1 subunit bound to ARF6(Q67L)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ADP-ribosylation factor 6 | polymer | 175 | 20095.2 | 1 | UniProt (P62330) Pfam (PF00025) In PDB | Homo sapiens (human) | |
2 | B | Cholera enterotoxin, A chain | polymer | 193 | 21710.8 | 1 | UniProt (P01555) Pfam (PF01375) In PDB | Vibrio cholerae | |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
5 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 2 - 175 (UniProt: P62330)
B: 1 - 192 (UniProt: P01555)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Leu 67 | Gln 66 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 0 | - | cloning artifact |
Asp 110 | Glu 128 | engineered mutation |
Asp 112 | Glu 130 | engineered mutation |
Ser 187 | Cys 205 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 41806.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 570.5 | |
All* | Total formula weight | 42376.4 |