2A5G
Cholera toxin A1 subunit bound to ARF6(Q67L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosylation factor 6 | polymer | 175 | 20095.2 | 1 | UniProt (P62330) Pfam (PF00025) | Homo sapiens (human) | |
| 2 | B (B) | Cholera enterotoxin, A chain | polymer | 193 | 21710.8 | 1 | UniProt (P01555) Pfam (PF01375) | Vibrio cholerae | |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | E (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 2 - 175 (UniProt: P62330)
B: 1 - 192 (UniProt: P01555)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Leu 67 | Gln 66 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | cloning artifact |
| Asp 110 | Glu 128 | engineered mutation |
| Asp 112 | Glu 130 | engineered mutation |
| Ser 187 | Cys 205 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41806.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 42376.4 |
