2A2K
Crystal Structure of an active site mutant, C473S, of Cdc25B Phosphatase Catalytic Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | M-phase inducer phosphatase 2 | polymer | 175 | 20665.7 | 1 | UniProt (P30305) Pfam (PF00581) | Homo sapiens (human) | Dual specificity phosphatase Cdc25B |
| 2 | B, C (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | E (A) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A: 377 - 550 (UniProt: P30305)
| PDB | External Database | Details |
|---|---|---|
| Met 376 | - | initiating methionine |
| Ser 473 | Cys 473 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20665.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 167.0 | |
| All* | Total formula weight | 20832.7 |
