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2A1J

Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA repair endonuclease XPFpolymer636964.01UniProt (Q92889)Homo sapiens (human)DNA excision repair protein ERCC-4, DNA-repair protein complementing XP-F cell, Xeroderma pigmentosum group F complementing protein
2B
(B)
DNA excision repair protein ERCC-1polymer9110205.61UniProt (P07992)
Pfam (PF00633)
Homo sapiens (human)
3C
(B)
MERCURY (II) IONnon-polymer200.61Chemie (HG)
Sequence modifications
A: 837 - 898 (UniProt: Q92889)
PDBExternal DatabaseDetails
Met 836-cloning artifact
B: 220 - 296 (UniProt: P07992)
PDBExternal DatabaseDetails
Met 206-cloning artifact
Gly 207-cloning artifact
Ser 208-cloning artifact
Ser 209-cloning artifact
His 210-expression tag
His 211-expression tag
His 212-expression tag
His 213-expression tag
His 214-expression tag
His 215-expression tag
Ser 216-cloning artifact
Gln 217-cloning artifact
Asp 218-cloning artifact
Pro 219-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight17169.6
Non-Polymers*Number of molecules1
Total formula weight200.6
All*Total formula weight17370.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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