2A0Z
The molecular structure of toll-like receptor 3 ligand binding domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Toll-like receptor 3 | polymer | 705 | 80315.1 | 1 | UniProt (O15455) Pfam (PF13855) Pfam (PF13516) Pfam (PF00560) Pfam (PF17968) In PDB | Homo sapiens (human) | CD283 antigen |
2 | B, C, D, F, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
3 | E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
4 | H, J | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
5 | I | alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G51945PF) | |||
6 | K | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G07375KG) | |||
7 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
8 | A | alpha-D-glucopyranose | non-polymer | 180.2 | 2 | Chemie (GLC) | |||
9 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
10 | A | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
11 | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence modifications
A: 22 - 703 (UniProt: O15455)
PDB | External Database | Details |
---|---|---|
Glu 704 | - | SEE REMARK 999 |
Asn 705 | - | SEE REMARK 999 |
Leu 706 | - | SEE REMARK 999 |
Tyr 707 | - | SEE REMARK 999 |
Phe 708 | - | SEE REMARK 999 |
Gln 709 | - | SEE REMARK 999 |
Gly 710 | - | SEE REMARK 999 |
Asp 711 | - | SEE REMARK 999 |
Tyr 712 | - | SEE REMARK 999 |
Lys 713 | - | SEE REMARK 999 |
Asp 714 | - | SEE REMARK 999 |
Asp 715 | - | SEE REMARK 999 |
Asp 716 | - | SEE REMARK 999 |
Asp 717 | - | SEE REMARK 999 |
Lys 718 | - | SEE REMARK 999 |
Gly 719 | - | expression tag |
Ser 720 | - | expression tag |
His 721 | - | expression tag |
His 722 | - | expression tag |
His 723 | - | expression tag |
His 724 | - | expression tag |
His 725 | - | expression tag |
His 726 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 80315.1 | |
Branched | Number of molecules | 10 |
Total formula weight | 5184.9 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 947.8 | |
All* | Total formula weight | 86447.8 |