2A0Y
Structure of human purine nucleoside phosphorylase H257D mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Purine nucleoside phosphorylase | polymer | 289 | 32161.8 | 1 | UniProt (P00491) Pfam (PF01048) | Homo sapiens (human) | Inosine phosphorylase, PNP |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one | non-polymer | 265.3 | 1 | Chemie (DIH) | |||
| 4 | E (A) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: P00491)
| PDB | External Database | Details |
|---|---|---|
| Asp 257 | His 257 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32161.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 457.4 | |
| All* | Total formula weight | 32619.2 |
