2A0Q
Structure of thrombin in 400 mM potassium chloride
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Thrombin, light chain | polymer | 30 | 3518.0 | 2 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | Coagulation factor II |
| 2 | B, D (B, D) | Thrombin, heavy chain | polymer | 257 | 29507.9 | 2 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II |
| 3 | E (B) | 2-acetamido-2-deoxy-alpha-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NDG) | |||
| 4 | F, H (B, D) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 5 | G (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
B, D: 16 - 245 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 77 | Arg 436 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 66051.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 334.9 | |
| All* | Total formula weight | 66386.7 |
