2Z62
Crystal structure of the TV3 hybrid of human TLR4 and hagfish VLRB.61
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Toll-like receptor 4, Variable lymphocyte receptor B | polymer | 276 | 31141.7 | 1 | UniProt (O00206) UniProt (Q4G1L2) Pfam (PF13855) Pfam (PF12799) Pfam (PF11921) | Homo sapiens (human inshore hagfish) | hToll, CD284 antigen, TV3 |
| 2 | B (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G86566TX) | |||
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G28454KX) | |||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (A) | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
A: 27 - 228 (UniProt: O00206)
A: 231 - 302 (UniProt: Q4G1L2)
| PDB | External Database | Details |
|---|---|---|
| Lys 229 | - | SEE REMARK 999 |
| Glu 230 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31141.7 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1727.6 | |
| All* | Total formula weight | 32869.3 |
