2GZD
Crystal Structure of Rab11 in Complex with Rab11-FIP2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ras-related protein Rab-11A | polymer | 173 | 19547.8 | 2 | UniProt (P62491) Pfam (PF00071) | Homo sapiens (human) | Rab-11, YL8 |
| 2 | C, D (C, D) | Rab11 family-interacting protein 2 | polymer | 107 | 12336.8 | 2 | UniProt (Q7L804) Pfam (PF09457) | Homo sapiens (human) | Rab11-FIP2, NRip11 |
| 3 | E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | F, H (A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 173 (UniProt: P62491)
C, D: 410 - 512 (UniProt: Q7L804)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | cloning artifact |
| Leu 70 | Gln 69 | engineered mutation |
| Mse 120 | Met 119 | modified residue |
| PDB | External Database | Details |
|---|---|---|
| Gly 406 | - | cloning artifact |
| Ala 407 | - | cloning artifact |
| Met 408 | - | cloning artifact |
| Ala 409 | - | cloning artifact |
| Mse 489 | Met 489 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 63769.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1095.0 | |
| All* | Total formula weight | 64864.3 |
