29ZZ
Human smooth muscle myosin motor domain co-crystallized with the S(-)2501 inhibitor, MgADP-VO4 form.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Myosin-11 | polymer | 794 | 90574.6 | 1 | UniProt (P35749) Pfam (PF02736) Pfam (PF00063) | Homo sapiens (human) | Myosin heavy chain 11,Myosin heavy chain,smooth muscle isoform,SMMHC |
| 2 | B (A) | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) PubChem (61672) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 6 | F, G, I, J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | H (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) PubChem (679) | |||
| 8 | K (A) | (9S)-12-[4-(dimethylamino)phenyl]-5-methyl-9-oxidanyl-4-thia-2,12-diazatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),5-trien-8-one | non-polymer | 341.4 | 1 | Chemie (A1IMH) | |||
| 9 | L (A) | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A: 1 - 785 (UniProt: P35749)
| PDB | External Database | Details |
|---|---|---|
| Gly 786 | - | expression tag |
| Asp 787 | - | expression tag |
| Tyr 788 | - | expression tag |
| Lys 789 | - | expression tag |
| Asp 790 | - | expression tag |
| Asp 791 | - | expression tag |
| Asp 792 | - | expression tag |
| Asp 793 | - | expression tag |
| Lys 794 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 90574.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1326.4 | |
| All* | Total formula weight | 91901.0 |
