29ZY
Human smooth muscle myosin motor domain co-crystallized with the R(+)2501 inhibitor, MgAMP-PNP form.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Myosin-11 | polymer | 794 | 90546.5 | 4 | UniProt (P35749) Pfam (PF02736) Pfam (PF00063) | Homo sapiens (human) | Myosin heavy chain 11,Myosin heavy chain,smooth muscle isoform,SMMHC |
| 2 | E, I, J, N, O... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) PubChem (888) | |||
| 3 | F, K, P, S (A, B, C, D) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 4 | Chemie (ANP) | |||
| 4 | G, L, Q, T (A, B, C, D) | (9R)-12-[4-(dimethylamino)phenyl]-5-methyl-9-oxidanyl-4-thia-2,12-diazatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),5-trien-8-one | non-polymer | 341.4 | 4 | Chemie (A1IMR) | |||
| 5 | H, M, U (A, B, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) PubChem (679) | |||
| 6 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 784 (UniProt: P35749)
| PDB | External Database | Details |
|---|---|---|
| Ala 785 | - | expression tag |
| Ser 786 | - | expression tag |
| Asp 787 | - | expression tag |
| Tyr 788 | - | expression tag |
| Lys 789 | - | expression tag |
| Asp 790 | - | expression tag |
| Asp 791 | - | expression tag |
| Asp 792 | - | expression tag |
| Asp 793 | - | expression tag |
| Lys 794 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 362186.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3770.7 | |
| All* | Total formula weight | 365956.8 |
