29TK
RNA polymerase II elongation complex with the +1 nucleosome
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | DNA-directed RNA polymerase II subunit RPB3 | polymer | 275 | 31439.1 | 1 | UniProt (I3LCH3) Pfam (PF01193) Pfam (PF01000) | Sus scrofa (pig) | |
| 2 | B (D) | RNA polymerase II subunit D | polymer | 184 | 20962.6 | 1 | UniProt (A0A287ADR4) Pfam (PF03874) | Sus scrofa (pig) | |
| 3 | C (E) | DNA-directed RNA polymerase II subunit E | polymer | 210 | 24644.3 | 1 | UniProt (I3LSI7) Pfam (PF03871) Pfam (PF01191) | Sus scrofa (pig) | RPB5 homolog |
| 4 | D (F) | DNA-directed RNA polymerases I, II, and III subunit RPABC2 | polymer | 127 | 14477.0 | 1 | UniProt (A0A8D1KNW4) | Sus scrofa (pig) | |
| 5 | E (G) | DNA-directed RNA polymerase subunit | polymer | 171 | 19227.2 | 1 | UniProt (A0A4X1VKG7) | Sus scrofa (pig) | |
| 6 | F (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (I3LCB2) Pfam (PF03870) | Sus scrofa (pig) | |
| 7 | G (I) | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14541.2 | 1 | UniProt (P60899) Pfam (PF02150) Pfam (PF01096) | Sus scrofa (pig) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5 |
| 8 | H (J) | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (A0A4X1VYD0) | Sus scrofa (pig) | |
| 9 | I (K) | DNA-directed RNA polymerase II subunit RPB11-a | polymer | 117 | 13310.3 | 1 | UniProt (F1RKE4) Pfam (PF13656) | Sus scrofa (pig) | |
| 10 | J (L) | RNA polymerase II subunit K | polymer | 58 | 7018.2 | 1 | UniProt (A0A8D0JYF1) | Sus scrofa (pig) | |
| 11 | K (P) | RNA (5'-R(P*AP*CP*AP*CP*CP*CP*AP*GP*CP*C)-3') | polymer | 10 | 3119.0 | 1 | unidentified adenovirus | ||
| 12 | L (Q) | General transcription factor IIF subunit 1 | polymer | 517 | 58343.6 | 1 | UniProt (P35269) Pfam (PF05793) | Homo sapiens (human) | General transcription factor IIF 74 kDa subunit,Transcription initiation factor IIF subunit alpha,TFIIF-alpha,Transcription initiation factor RAP74 |
| 13 | M (R) | General transcription factor IIF subunit 2 | polymer | 249 | 28427.3 | 1 | UniProt (P13984) Pfam (PF17683) Pfam (PF02270) | Homo sapiens (human) | ATP-dependent helicase GTF2F2,General transcription factor IIF 30 kDa subunit,Transcription initiation factor IIF subunit beta,TFIIF-beta,Transcription initiation factor RAP30 |
| 14 | N (T) | DNA (199-MER) | polymer | 252 | 77941.5 | 1 | unidentified adenovirus | ||
| 15 | O (W) | General transcription factor IIE subunit 1 | polymer | 439 | 49516.1 | 1 | UniProt (P29083) Pfam (PF02002) Pfam (PF08271) Pfam (PF11521) | Homo sapiens (human) | General transcription factor IIE 56 kDa subunit,Transcription initiation factor IIE subunit alpha,TFIIE-alpha |
| 16 | P, T (a, e) | Histone H3.2 | polymer | 136 | 15421.1 | 2 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 17 | Q, U (b, f) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 18 | R, V (c, g) | Histone H2A type 1 | polymer | 130 | 14093.4 | 2 | UniProt (P06897) Pfam (PF00125) Pfam (PF16211) | Xenopus laevis (African clawed frog) | |
| 19 | S, W (d, h) | Histone H2B 1.1 | polymer | 126 | 13965.3 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 20 | X (A) | DNA-directed RNA polymerase subunit | polymer | 1970 | 217450.1 | 1 | UniProt (A0A7M4DUC2) | Sus scrofa (pig) | |
| 21 | Y (B) | DNA-directed RNA polymerase subunit beta | polymer | 1300 | 147938.6 | 1 | UniProt (I3LGP4) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | Sus scrofa (pig) | |
| 22 | Z (N) | DNA (188-MER) | polymer | 252 | 77701.3 | 1 | unidentified adenovirus | ||
| 23 | AA, BA, CA, DA, EA... (C, I, J, L, W...) | ZINC ION | non-polymer | 65.4 | 9 | Chemie (ZN) PubChem (32051) | |||
| 24 | GA (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) |
Sequence modifications
c, g: 1 - 130 (UniProt: P06897)
A: 1 - 1970 (UniProt: A0A7M4DUC2)
| PDB | External Database | Details |
|---|---|---|
| Arg 100 | Gly 100 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| - | Tyr 1636 | deletion |
| - | Ser 1637 | deletion |
| - | Pro 1638 | deletion |
| - | Thr 1639 | deletion |
| - | Ser 1640 | deletion |
| - | Pro 1641 | deletion |
| - | Ser 1642 | deletion |
| - | Tyr 1643 | deletion |
| - | Ser 1644 | deletion |
| - | Pro 1645 | deletion |
| - | Thr 1646 | deletion |
| - | Ser 1647 | deletion |
| - | Pro 1648 | deletion |
| - | Ser 1649 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 26 |
| Total formula weight | 940623.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 613.0 | |
| All* | Total formula weight | 941236.3 |
