29MX
Crystal structure of the Dihydrofolate reductase from Nocardia asteroides bound to NADPH and trimethoprim
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 161 | 17589.8 | 1 | UniProt (U5E929) Pfam (PF00186) | Nocardia asteroides NBRC 15531 | |
| 2 | B (A) | TRIMETHOPRIM | non-polymer | 290.3 | 1 | Chemie (TOP) PubChem (5578) | |||
| 3 | C (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 4 | D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | G (A) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17589.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1323.9 | |
| All* | Total formula weight | 18913.8 |
