28ZT
Crystal structure of human DHX9 in complex with ATX-968 and ADP
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ATP-dependent RNA helicase A | polymer | 1010 | 114340.2 | 4 | UniProt (Q08211) | Homo sapiens (human) | DEAH box protein 9,DExH-box helicase 9,Leukophysin,LKP,Nuclear DNA helicase II,NDH II,RNA helicase A |
| 2 | E, H, K, N (A, B, C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 3 | F, I, L, O (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 4 | G, J, M (A, B, C) | (4M)-N-[3-chloro-5-(methanesulfonamido)phenyl]-4-(3-methylpyridin-2-yl)thiophene-2-carboxamide | non-polymer | 421.9 | 3 | Chemie (A1BKX) PubChem (169144997) | |||
| 5 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 150 - 1150 (UniProt: Q08211)
| PDB | External Database | Details |
|---|---|---|
| Met 149 | - | initiating methionine |
| Asp 1151 | - | expression tag |
| Tyr 1152 | - | expression tag |
| Lys 1153 | - | expression tag |
| Asp 1154 | - | expression tag |
| Asp 1155 | - | expression tag |
| Asp 1156 | - | expression tag |
| Asp 1157 | - | expression tag |
| Lys 1158 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 457360.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3071.8 | |
| All* | Total formula weight | 460432.4 |
