28ZB
Crystal Structure of HLA class II major histocompatibility complex bound to HCMV-IE1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, D, G, J) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 202 | 23492.3 | 4 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | MHC class II antigen DRA |
| 2 | B, D, F, H (B, E, H, K) | Regulatory protein IE1,HLA class II histocompatibility antigen DR beta chain | polymer | 239 | 27135.2 | 4 | UniProt (Q5Y7D1) Pfam (PF00969) Pfam (PF07654) | Human cytomegalovirus | HLA-DRB1 protein,MHC class II antigen,Major histocompatibility complex,class II,DR beta 1 |
| 3 | I, J, M, N, P (A, B, E, H) | PHOSPHATE ION | non-polymer | 95.0 | 5 | Chemie (PO4) PubChem (1061) | |||
| 4 | K, L, O, Q (D, E, G, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) PubChem (24139) | |||
| 5 | R, S, T, U, V... (A, B, D, E, G...) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A, D, G, J: 26 - 216 (UniProt: P01903)
B, E, H, K: -30 - -16 (PDB: 28ZB)
B, E, H, K: 30 - 219 (UniProt: Q5Y7D1)
| PDB | External Database | Details |
|---|---|---|
| Asp 217 | - | expression tag |
| Asp 218 | - | expression tag |
| Asp 219 | - | expression tag |
| Asp 220 | - | expression tag |
| Lys 221 | - | expression tag |
| Glu 222 | - | expression tag |
| Asn 223 | - | expression tag |
| Leu 224 | - | expression tag |
| Tyr 225 | - | expression tag |
| Phe 226 | - | expression tag |
| Gln 227 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | linker |
| Gly 16 | - | linker |
| Gly 17 | - | linker |
| Gly 18 | - | linker |
| Ser 19 | - | linker |
| Gly 20 | - | linker |
| Gly 21 | - | linker |
| Gly 22 | - | linker |
| Gly 23 | - | linker |
| Ser 24 | - | linker |
| Gly 25 | - | linker |
| Gly 26 | - | linker |
| Gly 27 | - | linker |
| Gly 28 | - | linker |
| Ser 29 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 220 | - | expression tag |
| Glu 221 | - | expression tag |
| Thr 222 | - | expression tag |
| Val 223 | - | expression tag |
| Pro 224 | - | expression tag |
| Arg 225 | - | expression tag |
| Ser 226 | - | expression tag |
| Gly 227 | - | expression tag |
| Glu 228 | - | expression tag |
| Val 229 | - | expression tag |
| Tyr 230 | - | expression tag |
| Thr 231 | - | expression tag |
| Cys 232 | - | expression tag |
| Gln 233 | - | expression tag |
| Val 234 | - | expression tag |
| Glu 235 | - | expression tag |
| His 236 | - | expression tag |
| Pro 237 | - | expression tag |
| Ser 238 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 202509.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1359.7 | |
| All* | Total formula weight | 203869.6 |
