28RW
Crystal structure of the carbohydrate-recognition domain of R144S galectin-3 mutant in apo form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Galectin-3 | polymer | 142 | 15947.3 | 1 | UniProt (P17931) Pfam (PF00337) | Homo sapiens (human) | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
| 2 | B (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) PubChem (3777159) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 5 | E (A) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 112 - 250 (UniProt: P17931)
| PDB | External Database | Details |
|---|---|---|
| Gly 109 | - | expression tag |
| Ala 110 | - | expression tag |
| Met 111 | - | expression tag |
| Ser 144 | Arg 144 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15947.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 180.6 | |
| All* | Total formula weight | 16127.9 |
