28MQ
Cryo-EM structure of UBA6-FAT10Dha-UBE2Z trapped ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-conjugating enzyme E2 Z | polymer | 356 | 38403.3 | 1 | UniProt (Q9H832) | Homo sapiens (human) | E2 ubiquitin-conjugating enzyme Z,Uba6-specific E2 conjugating enzyme 1,Use1,Ubiquitin carrier protein Z,Ubiquitin-protein ligase Z |
| 2 | B (B) | Ubiquitin-like modifier-activating enzyme 6 | polymer | 1054 | 118266.9 | 1 | UniProt (A0AVT1) | Homo sapiens (human) | Ubiquitin-activating enzyme 6,Monocyte protein 4,MOP-4,Ubiquitin-activating enzyme E1-like protein 2,E1-L2 |
| 3 | C (C) | Ubiquitin D | polymer | 167 | 18644.7 | 1 | UniProt (O15205) | Homo sapiens (human) | Diubiquitin,Ubiquitin-like protein FAT10 |
| 4 | D (B) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) |
Sequence modifications
A: 1 - 354 (UniProt: Q9H832)
B: 1 - 1052 (UniProt: A0AVT1)
C: 1 - 165 (UniProt: O15205)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Thr 7 | Cys 7 | engineered mutation |
| Thr 9 | Cys 9 | engineered mutation |
| Leu 134 | Cys 134 | engineered mutation |
| Ser 160 | Cys 160 | engineered mutation |
| Ser 162 | Cys 162 | engineered mutation |
| Ala 165 | Gly 165 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 175314.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 660.0 | |
| All* | Total formula weight | 175974.8 |
