28MO
Cryo-EM structure of UBA6-UbDha-UBE2Z trapped ternary complex (singly loaded)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-conjugating enzyme E2 Z | polymer | 356 | 38403.3 | 1 | UniProt (Q9H832) | Homo sapiens (human) | E2 ubiquitin-conjugating enzyme Z,Uba6-specific E2 conjugating enzyme 1,Use1,Ubiquitin carrier protein Z,Ubiquitin-protein ligase Z |
| 2 | B (B) | Ubiquitin-like modifier-activating enzyme 6 | polymer | 1054 | 118250.8 | 1 | UniProt (A0AVT1) | Homo sapiens (human) | Ubiquitin-activating enzyme 6,Monocyte protein 4,MOP-4,Ubiquitin-activating enzyme E1-like protein 2,E1-L2 |
| 3 | C (C) | Polyubiquitin-B | polymer | 76 | 8590.9 | 1 | UniProt (P0CG47) | Homo sapiens (human) | |
| 4 | D (B) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 5 | E (B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence modifications
A: 1 - 354 (UniProt: Q9H832)
B: 1 - 1052 (UniProt: A0AVT1)
C: 1 - 76 (UniProt: P0CG47)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ser 625 | Cys 625 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 76 | Gly 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 165244.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1167.2 | |
| All* | Total formula weight | 166412.1 |
