27IQ
Crystal structure of the mature form of human ASPRV1 bound to filaggrin peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Retroviral-like aspartic protease 1 | polymer | 142 | 15446.7 | 2 | UniProt (Q53RT3) Pfam (PF13975) | Homo sapiens (human) | Skin-specific retroviral-like aspartic protease,SASPase,Skin aspartic protease,TPA-inducible aspartic proteinase-like protein,TAPS |
| 2 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A, B: 191 - 321 (UniProt: Q53RT3)
| PDB | External Database | Details |
|---|---|---|
| Ser 190 | - | expression tag |
| Asn 212 | Asp 212 | conflict |
| Gly 322 | - | expression tag |
| Ser 323 | - | expression tag |
| Phe 324 | - | expression tag |
| Leu 325 | - | expression tag |
| Tyr 326 | - | expression tag |
| Gln 327 | - | expression tag |
| Val 328 | - | expression tag |
| Ser 329 | - | expression tag |
| Thr 330 | - | expression tag |
| His 331 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30893.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 30973.5 |
