27EB
TCR-HLA-DQ2.5-glia-w2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | HLA class II histocompatibility antigen, DQ alpha 1 chain | polymer | 190 | 21432.9 | 2 | UniProt (P01909) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | DC-1 alpha chain,DC-alpha,HLA-DCA,MHC class II DQA1 |
| 2 | B, E (B, E) | cDNA FLJ59004, highly similar to HLA class II histocompatibility antigen, DQ(1)beta chain | polymer | 200 | 23287.1 | 2 | UniProt (B4E328) | Homo sapiens (human) | HLA class II histocompatibility antigen, DQ 2.5 beta chain |
| 3 | C, F (C, F) | glia-omega 2 peptide | polymer | 12 | 1427.6 | 2 | Homo sapiens | ||
| 4 | G, I (G, I) | TCR alpha chain | polymer | 207 | 23302.8 | 2 | Homo sapiens | ||
| 5 | H, J (H, J) | TCR beta chain | polymer | 241 | 27208.0 | 2 | Homo sapiens | ||
| 6 | K, L (K, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 7 | M, P, Q, R, S (A, G, H, I, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) PubChem (24139) | |||
| 8 | N, O (D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 9 | T, U, V, W, X... (A, B, D, E, G...) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, D: -1 - 180 (UniProt: P01909)
B, E: 37 - 228 (UniProt: B4E328)
| PDB | External Database | Details |
|---|---|---|
| Cys 71 | Ser 97 | conflict |
| Ser 181 | - | expression tag |
| Gly 182 | - | expression tag |
| Asp 183 | - | expression tag |
| Asp 184 | - | expression tag |
| Asp 185 | - | expression tag |
| Asp 186 | - | expression tag |
| Lys 187 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Thr 229 | - | expression tag |
| Gly 230 | - | expression tag |
| Gly 231 | - | expression tag |
| Asp 232 | - | expression tag |
| Asp 233 | - | expression tag |
| Asp 234 | - | expression tag |
| Asp 235 | - | expression tag |
| Lys 236 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 193316.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1290.2 | |
| All* | Total formula weight | 195455.6 |
