26XH
Cryo-EM structure of Maleic Acid bound OXGR1-Gq complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G protein subunit q | polymer | 361 | 41632.2 | 1 | Homo sapiens (human) | ||
| 2 | B (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) | Homo sapiens (human) | G gamma-I |
| 3 | C (N) | Nanobody35 | polymer | 138 | 15140.7 | 1 | Lama glama | ||
| 4 | D (R) | 2-oxoglutarate receptor 1 | polymer | 337 | 38284.0 | 1 | UniProt (Q96P68) | Homo sapiens (human) | Alpha-ketoglutarate receptor 1,G-protein coupled receptor 80,G-protein coupled receptor 99,P2Y purinoceptor 15,P2Y15,P2Y-like GPCR,P2Y-like nucleotide receptor |
| 5 | E (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 351 | 38744.4 | 1 | UniProt (P62873) | Homo sapiens (human) | Transducin beta chain 1 |
| 6 | F (S) | scFv16 | polymer | 247 | 26293.3 | 1 | Homo sapiens (human) | ||
| 7 | G (R) | MALEIC ACID | non-polymer | 116.1 | 1 | Chemie (MAE) PubChem (444266) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | initiating methionine |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 167955.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 116.1 | |
| All* | Total formula weight | 168071.9 |
