26JD
Cryo-EM ternary structure of CD1c presenting a mycobacterial lipid to a T cell receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | T-cell surface glycoprotein CD1c | polymer | 275 | 31056.8 | 1 | UniProt (P29017) | Homo sapiens (human) | |
| 2 | B (B) | MPM7 T cell receptor beta chain | polymer | 249 | 28421.6 | 1 | Homo sapiens | ||
| 3 | C (A) | MPM7 T cell receptor alpha chain | polymer | 202 | 22692.2 | 1 | Homo sapiens | ||
| 4 | D (D) | Beta-2-microglobulin | polymer | 98 | 11617.0 | 1 | UniProt (P61769) | Homo sapiens (human) | |
| 5 | E, F, G (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) PubChem (24139) | |||
| 6 | H (C) | (4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl dihydrogen phosphate | non-polymer | 546.8 | 1 | Chemie (Z7B) PubChem (131801227) | |||
| 7 | I (C) | N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)STEARAMIDE | non-polymer | 566.0 | 1 | Chemie (18C) PubChem (5283565) |
Sequence modifications
C: 6 - 279 (UniProt: P29017)
| PDB | External Database | Details |
|---|---|---|
| Ser 280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93787.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1776.4 | |
| All* | Total formula weight | 95563.9 |
