26BE
X-ray crystal structure of human NBS1 FHA-BRCT1-BRCT2 domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Nibrin | polymer | 334 | 37234.6 | 4 | UniProt (O60934) Pfam (PF00498) Pfam (PF00533) Pfam (PF16508) | Homo sapiens (human) | Cell cycle regulatory protein p95,Nijmegen breakage syndrome protein 1,hNbs1 |
| 2 | E, H, N, Q (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) PubChem (1061) | |||
| 3 | F, I, O, P, R (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | G, J, K, L, M... (A, B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | T, U, V, W (A, B, C, D) | water | water | 18.0 | 422 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 326 (UniProt: O60934)
| PDB | External Database | Details |
|---|---|---|
| Leu 327 | - | expression tag |
| Glu 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| His 333 | - | expression tag |
| His 334 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 148938.4 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1232.6 | |
| All* | Total formula weight | 150171.0 |
