25YS
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase on rat synaptic vesicles, state 3
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | V-type proton ATPase subunit S1 | polymer | 463 | 51160.4 | 1 | UniProt (O54715) Pfam (PF05827) Pfam (PF20520) | Rattus norvegicus (Norway rat) | V-ATPase subunit S1,C7-1 protein,V-ATPase Ac45 subunit,V-ATPase S1 accessory protein,Vacuolar proton pump subunit S1 |
| 2 | B (b) | V-type proton ATPase 21 kDa proteolipid subunit c'' | polymer | 205 | 21618.6 | 1 | UniProt (B0K022) | Rattus norvegicus (Norway rat) | Vacuolar proton pump 21 kDa proteolipid subunit c'' |
| 3 | C (d) | V-type proton ATPase subunit | polymer | 351 | 40341.9 | 1 | UniProt (Q5M7T6) | Rattus norvegicus (Norway rat) | |
| 4 | D (e) | V-type proton ATPase subunit e 2 | polymer | 81 | 9203.0 | 1 | UniProt (Q5EB76) Pfam (PF05493) | Rattus norvegicus (Norway rat) | V-ATPase subunit e 2,Vacuolar proton pump subunit e 2 |
| 5 | E (f) | Ribonuclease K | polymer | 98 | 11000.0 | 1 | UniProt (D3ZIM6) | Rattus norvegicus (Norway rat) | Rnasek protein |
| 6 | F, G, H, I, J... (h, i, j, k, l...) | V-type proton ATPase 16 kDa proteolipid subunit c | polymer | 155 | 15815.8 | 9 | UniProt (P63081) Pfam (PF00137) | Rattus norvegicus (Norway rat) | V-ATPase 16 kDa proteolipid subunit c,Vacuolar proton pump 16 kDa proteolipid subunit c |
| 7 | N (p) | Renin receptor | polymer | 350 | 39118.6 | 1 | UniProt (Q6AXS4) Pfam (PF25294) Pfam (PF07850) | Rattus norvegicus (Norway rat) | ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,Renin/prorenin receptor |
| 8 | P (H) | V-type proton ATPase subunit D | polymer | 226 | 26094.3 | 1 | UniProt (Q6P503) Pfam (PF01813) | Rattus norvegicus (Norway rat) | V-type proton ATPase subunit d,Vacuolar proton pump subunit D |
| 9 | Q (a) | V-type proton ATPase 116 kDa subunit a 1 | polymer | 838 | 96429.4 | 1 | UniProt (P25286) Pfam (PF01496) | Rattus norvegicus (Norway rat) | V-ATPase 116 kDa subunit a 1,Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit,Vacuolar adenosine triphosphatase subunit Ac116,Vacuolar proton pump subunit 1,Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 |
| 10 | R (Z) | alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1559.4 | 1 | In PDB GlyTouCan (G44289EY) | |||
| 11 | RA, RB, S, T, U (k, a, P, b) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 5 | Chemie (PC1) | |||
| 12 | IA, MB, NB, SB, TB... (j, p, a, b, e) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 9 | Chemie (PTY) | |||
| 13 | AB, BA, BB, CA, EA... (m, h, i, n, o...) | CHOLESTEROL | non-polymer | 386.7 | 30 | Chemie (CLR) PubChem (5997) | |||
| 14 | AA, CB, DA, DB, NA... (h, n, i, k, a...) | concanamycin A | non-polymer | 866.1 | 8 | Chemie (A1MGD) | |||
| 15 | PB (a) | methyl (3R,6Z,10E,14E)-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraen-1-yl dihydrogen diphosphate | non-polymer | 534.6 | 1 | Chemie (WJP) | |||
| 16 | QB (a) | (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE | non-polymer | 524.7 | 1 | Chemie (LP3) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 17 |
| Total formula weight | 437308.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1559.4 | |
| Non-Polymers* | Number of molecules | 54 |
| Total formula weight | 30144.7 | |
| All* | Total formula weight | 469012.8 |






