25RG
CyroEM structure of the complex between Shiga toxin Stx1a B subunit and neutralising Fab fragment of RDS045
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J, M (A, D, E, F, G) | Shiga toxin subunit B | polymer | 73 | 8031.0 | 5 | UniProt (Q32GM0) | Shigella dysenteriae | |
| 2 | B, E, H, K, N (B, H, I, J, K) | Heavy chain of RDS045 Fab | polymer | 220 | 23474.2 | 5 | Homo sapiens (human) | ||
| 3 | C, F, I, L, O (C, L, M, N, O) | Light chain of RDS045 Fab | polymer | 216 | 23650.3 | 5 | Homo sapiens (human) |
Sequence modifications
A, D, E, F, G: 2 - 70 (UniProt: Q32GM0)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 71 | - | expression tag |
| Ser 72 | - | expression tag |
| Gly 73 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 275777.5 | |
| All* | Total formula weight | 275777.5 |
