25EC
Crystal Structure of a Human Topoisomerase II Beta-DNA Cleavage Complex Trapped in N-gate Dissociated State
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | DNA topoisomerase 2-beta | polymer | 757 | 86811.9 | 1 | UniProt (Q02880) Pfam (PF01751) Pfam (PF16898) Pfam (PF00521) | Homo sapiens (human) | DNA topoisomerase II,beta isozyme |
| 2 | B (D) | DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3') | polymer | 12 | 3654.4 | 1 | Nonea | ||
| 3 | C (E) | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3') | polymer | 8 | 2436.6 | 1 | Nonea | ||
| 4 | D, E, J (B, D) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) | |||
| 5 | F, G, H, I (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | K, L (B, D) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 92902.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 321.2 | |
| All* | Total formula weight | 93224.1 |
