24WC
Crystal structure of Haspin (GSG2) with an ATP-mimicking inhibitor LJ-5242
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase haspin | polymer | 342 | 38886.5 | 1 | UniProt (Q8TF76) Pfam (PF12330) | Homo sapiens (human) | Germ cell-specific gene 2 protein,H-haspin,Haploid germ cell-specific nuclear protein kinase |
| 2 | B (A) | 4-azanyl-7-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-[(sulfamoylamino)methyl]thiolan-2-yl]-5-ethynyl-pyrrolo[2,3-d]pyrimidine | non-polymer | 384.4 | 1 | Chemie (A1MFT) | |||
| 3 | C (A) | water | water | 18.0 | 436 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38886.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 39270.9 |
