24VA

Cryo-EM structure of recombinant Botulinum neurotoxin A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Botulinum neurotoxin type A	polymer	448	51225.0	1	UniProt (P0DPI1)	Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)	BoNT/A,Bontoxilysin-A,BOTOX
2	B (B)	Botulinum neurotoxin A heavy chain	polymer	850	98404.1	1	UniProt (P0DPI1)	Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)	HC

Sequence modifications

A: 6 - 442 (UniProt: P0DPI1)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag
Leu 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag
Leu 443	-	expression tag
Glu 444	-	expression tag
Val 445	-	expression tag
Leu 446	-	expression tag
Phe 447	-	expression tag
Gln 448	-	expression tag

B: 3 - 850 (UniProt: P0DPI1)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	149629.2
All*	Total formula weight	149629.2

*Water molecules are not included.