24KR
Structural basis of influenza A virus neutralization by broadly active single-domain antibody G2.3 recognizing glycosylated epitope within hemagglutinin stem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, B, C) | Hemagglutinin | polymer | 567 | 63447.1 | 3 | UniProt (C3W5S1) | Influenza A virus (A/California/04/2009(H1N1)) | |
| 2 | B, D, F (D, E, F) | Heavy chain antibody G2.3-Fc | polymer | 400 | 44188.2 | 3 | synthetic construct | ||
| 3 | G, H, I, J, K... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A, B, C: -16 - 501 (UniProt: C3W5S1)
| PDB | External Database | Details |
|---|---|---|
| Ser 502 | - | expression tag |
| Gly 503 | - | expression tag |
| Gly 504 | - | expression tag |
| Gly 505 | - | expression tag |
| Gly 506 | - | expression tag |
| Arg 507 | - | expression tag |
| Leu 508 | - | expression tag |
| Val 509 | - | expression tag |
| Pro 510 | - | expression tag |
| Arg 511 | - | expression tag |
| Gly 512 | - | expression tag |
| Ser 513 | - | expression tag |
| Pro 514 | - | expression tag |
| Gly 515 | - | expression tag |
| Ser 516 | - | expression tag |
| Gly 517 | - | expression tag |
| Tyr 518 | - | expression tag |
| Ile 519 | - | expression tag |
| Pro 520 | - | expression tag |
| Glu 521 | - | expression tag |
| Ala 522 | - | expression tag |
| Pro 523 | - | expression tag |
| Arg 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Gly 526 | - | expression tag |
| Gln 527 | - | expression tag |
| Ala 528 | - | expression tag |
| Tyr 529 | - | expression tag |
| Val 530 | - | expression tag |
| Arg 531 | - | expression tag |
| Lys 532 | - | expression tag |
| Asp 533 | - | expression tag |
| Gly 534 | - | expression tag |
| Glu 535 | - | expression tag |
| Trp 536 | - | expression tag |
| Val 537 | - | expression tag |
| Leu 538 | - | expression tag |
| Leu 539 | - | expression tag |
| Ser 540 | - | expression tag |
| Thr 541 | - | expression tag |
| Phe 542 | - | expression tag |
| Leu 543 | - | expression tag |
| Gly 544 | - | expression tag |
| His 545 | - | expression tag |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 322905.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3318.1 | |
| All* | Total formula weight | 326224.0 |
