24KM
Crystal structure of the first bromodomain (BD1) of human BRD4 in complex with Nimesulide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 128 | 15229.6 | 1 | UniProt (O60885) | Homo sapiens (human) | Protein HUNK1 |
| 2 | B (A) | 4-NITRO-2-PHENOXYMETHANESULFONANILIDE | non-polymer | 308.3 | 1 | Chemie (NIM) | |||
| 3 | C (A) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Phe 41 | - | expression tag |
| Gln 42 | - | expression tag |
| Met 43 | - | expression tag |
| Ala 163 | Glu 163 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15229.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 308.3 | |
| All* | Total formula weight | 15537.9 |
