24KK
Crystal structure of the second bromodomain (BD2) of human BRD2 in complex with Mefanamic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 2 | polymer | 114 | 13291.2 | 1 | UniProt (P25440) | Homo sapiens (human) | O27.1.1 |
| 2 | B (A) | 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID | non-polymer | 241.3 | 1 | Chemie (ID8) | |||
| 3 | C (A) | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
A: 348 - 454 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Ala 341 | - | expression tag |
| Ala 342 | - | expression tag |
| His 343 | - | expression tag |
| Gly 344 | - | expression tag |
| Ser 345 | - | expression tag |
| Asn 346 | - | expression tag |
| Pro 347 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13291.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 241.3 | |
| All* | Total formula weight | 13532.5 |
