24JU
Crystal structure of voltage-gated sodium channel NavAb N49K mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ion transport protein | polymer | 229 | 26597.9 | 1 | UniProt (A8EVM5) Pfam (PF00520) | Aliarcobacter butzleri RM4018 | |
| 2 | B (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) PubChem (114880) | |||
| 3 | C (A) | CHAPSO | non-polymer | 631.9 | 1 | Chemie (1N7) PubChem (90479263) | |||
| 4 | D, E, F, G, H... (A) | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 8 | Chemie (PX4) |
Sequence modifications
A: 1001 - 1229 (UniProt: A8EVM5)
| PDB | External Database | Details |
|---|---|---|
| Lys 1049 | Asn 49 | engineered mutation |
| Phe 1176 | Leu 176 | conflict |
| Ala 1206 | Thr 206 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26597.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 6574.0 | |
| All* | Total formula weight | 33171.9 |
