24IP

Cryo-EM structure of the dimeric WDR11-FAM91A1-C17orf75 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (D, A)	WD repeat-containing protein 11	polymer	1238	138330.9	2	UniProt (Q9BZH6)	Homo sapiens (human)	Bromodomain and WD repeat-containing protein 2,WD repeat-containing protein 15
2	B, E (C, F)	Protein Njmu-R1	polymer	410	46157.9	2	UniProt (Q9HAS0)	Homo sapiens (human)
3	D, F (B, E)	Protein FAM91A1	polymer	851	95433.4	2	UniProt (Q658Y4)	Homo sapiens (human)

Sequence modifications

D, A: 1 - 1224 (UniProt: Q9BZH6)

PDB	External Database	Details
Met -13	-	initiating methionine
Ala -12	-	expression tag
Ser -11	-	expression tag
Asp -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Lys -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

C, F: 1 - 396 (UniProt: Q9HAS0)

PDB	External Database	Details
Met -13	-	initiating methionine
Ala -12	-	expression tag
Ser -11	-	expression tag
Asp -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Lys -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

B, E: 1 - 838 (UniProt: Q658Y4)

PDB	External Database	Details
Met -12	-	initiating methionine
Gly -11	-	expression tag
Tyr -10	-	expression tag
Pro -9	-	expression tag
Tyr -8	-	expression tag
Asp -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Asp -4	-	expression tag
Tyr -3	-	expression tag
Ala -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	559844.4
All*	Total formula weight	559844.4

*Water molecules are not included.