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23VY

Crystal structure of the mouse RORalpha ligand binding domain in fusion with an NRIP1 LXXLL peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Nuclear receptor ROR-alpha,undecapeptidepolymer26430550.42UniProt (P51448)Mus musculus (house mouse)Nuclear receptor RZR-alpha,Nuclear receptor subfamily 1 group F member 1,RAR-related orphan receptor A,Retinoid-related orphan receptor-alpha
2C, D
(A, B)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
3E, F
(A, B)
waterwater18.06Chemie (HOH)
Sequence modifications
A, B: 269 - 514 (UniProt: P51448)
PDBExternal DatabaseDetails
Gly 264-expression tag
Ser 265-expression tag
Ala 266-expression tag
Met 267-expression tag
Gly 268-expression tag
Gly 515-linker
Gly 516-linker
A, B: 1001 - 1011 (PDB: 23VY)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight61100.8
Non-Polymers*Number of molecules2
Total formula weight773.3
All*Total formula weight61874.1
*Water molecules are not included.

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PDB entries from 2026-03-11

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