23KX
Regnase-1 PIN bound to suramin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Endoribonuclease ZC3H12A | polymer | 175 | 20482.6 | 2 | UniProt (Q5D1E7) Pfam (PF11977) | Mus musculus (house mouse) | Monocyte chemotactic protein-induced protein 1,MCP-induced protein 1,MCPIP-1,Regnase-1,Reg1,Zinc finger CCCH domain-containing protein 12A |
| 2 | C, E (A, B) | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID | non-polymer | 1297.3 | 2 | Chemie (SVR) PubChem (5361) | |||
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B: 134 - 305 (UniProt: Q5D1E7)
| PDB | External Database | Details |
|---|---|---|
| Pro 131 | - | expression tag |
| His 132 | - | expression tag |
| Met 133 | - | expression tag |
| Asn 226 | Asp 226 | engineered mutation |
| Asn 244 | Asp 244 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40965.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2643.2 | |
| All* | Total formula weight | 43608.4 |
