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23JW

Crystal structure of human cytosolic NADP(+)-dependent malic enzyme in a ternary complex with NADP+ and Mn2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, C, B, D)
NADP-dependent malic enzymepolymer57264223.44UniProt (P48163)
Pfam (PF00390)
Pfam (PF03949)
Homo sapiens (human)NADP-ME,Malic enzyme 1
2E, G, I, K
(A, C, B, D)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.44Chemie (NAP)
3F, H, J, L
(A, C, B, D)
MANGANESE (II) IONnon-polymer54.94Chemie (MN)
PubChem (27854)
4M, N, O, P
(A, C, B, D)
waterwater18.0265Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight256893.5
Non-Polymers*Number of molecules8
Total formula weight3193.4
All*Total formula weight260086.9
*Water molecules are not included.

260896

PDB entries from 2026-10-14

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