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23IW

Cannabinoid Receptor 1-Gi Complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(R)
Cannabinoid receptor 1polymer50456612.11UniProt (P21554)Homo sapiens (human)CB-R,CB1,CANN6
2B
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440414.01UniProt (P63096)Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
3C
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer33937285.71UniProt (P62873)Homo sapiens (human)Transducin beta chain 1
4D
(G)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)Homo sapiens (human)G gamma-I
5E
(S)
Scfv16polymer25026610.61Mus musculus
6F
(R)
methyl (2~{S},3~{R})-2-[[1-[(4-fluorophenyl)methyl]indazol-3-yl]carbonylamino]-3-oxidanyl-butanoatenon-polymer385.41Chemie (A1E5T)
Sequence modifications
R: 1 - 472 (UniProt: P21554)
PDBExternal DatabaseDetails
Met -31-initiating methionine
Lys -30-expression tag
Thr -29-expression tag
Ile -28-expression tag
Ile -27-expression tag
Ala -26-expression tag
Leu -25-expression tag
Ser -24-expression tag
Tyr -23-expression tag
Ile -22-expression tag
Phe -21-expression tag
Cys -20-expression tag
Leu -19-expression tag
Val -18-expression tag
Phe -17-expression tag
Ala -16-expression tag
Asp -15-expression tag
Tyr -14-expression tag
Lys -13-expression tag
Asp -12-expression tag
Asp -11-expression tag
Asp -10-expression tag
Asp -9-expression tag
Lys -8-expression tag
Leu -7-expression tag
Glu -6-expression tag
Val -5-expression tag
Leu -4-expression tag
Phe -3-expression tag
Gln -2-expression tag
Gly -1-expression tag
Pro 0-expression tag
A: 1 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Asn 47Ser 47engineered mutation
Ala 203Gly 203engineered mutation
Ala 245Glu 245engineered mutation
Ser 326Ala 326engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight168783.6
Non-Polymers*Number of molecules1
Total formula weight385.4
All*Total formula weight169169.0
*Water molecules are not included.

253795

PDB entries from 2026-05-20

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