23IVEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40414.0 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 339 | 37285.7 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (S) | Scfv16 | polymer | 250 | 26610.6 | 1 | Mus musculus | ||
| 5 | E (D) | Cannabinoid receptor 1 | polymer | 504 | 56612.1 | 1 | UniProt (P21554) Pfam (PF00001) | Homo sapiens (human) | CB-R,CB1,CANN6 |
| 6 | F (D) | methyl 1-[[1-[(4-fluorophenyl)methyl]indazol-3-yl]carbonylamino]cyclopropane-1-carboxylate | non-polymer | 367.4 | 1 | Chemie (A1E5S) |
Sequence modifications
A: 1 - 354 (UniProt: P63096)
D: 1 - 472 (UniProt: P21554)
| PDB | External Database | Details |
|---|---|---|
| Asn 47 | Ser 47 | engineered mutation |
| Ala 203 | Gly 203 | engineered mutation |
| Ala 245 | Glu 245 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met -31 | - | initiating methionine |
| Lys -30 | - | expression tag |
| Thr -29 | - | expression tag |
| Ile -28 | - | expression tag |
| Ile -27 | - | expression tag |
| Ala -26 | - | expression tag |
| Leu -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Tyr -23 | - | expression tag |
| Ile -22 | - | expression tag |
| Phe -21 | - | expression tag |
| Cys -20 | - | expression tag |
| Leu -19 | - | expression tag |
| Val -18 | - | expression tag |
| Phe -17 | - | expression tag |
| Ala -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Tyr -14 | - | expression tag |
| Lys -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Lys -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 168783.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 367.4 | |
| All* | Total formula weight | 169151.0 |
