23BB
Caspase-4 p20/p10 and human GSDMD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, E) | Caspase-4 | polymer | 166 | 19026.8 | 2 | UniProt (P49662) Pfam (PF00656) | Homo sapiens (human) | Caspase-4 p20,CASP-4,ICE and Ced-3 homolog 2,ICH-2,ICE(rel)-II,Mih1,Protease TX |
| 2 | C, D (C, D) | Caspase-4 | polymer | 88 | 10424.0 | 2 | UniProt (P49662) Pfam (PF00656) | Homo sapiens (human) | CASP-4,ICE and Ced-3 homolog 2,ICH-2,ICE(rel)-II,Mih1,Protease TX |
| 3 | E (A) | Gasdermin-D | polymer | 484 | 52851.8 | 1 | UniProt (P57764) Pfam (PF04598) Pfam (PF17708) | Homo sapiens (human) | Gasdermin domain-containing protein 1 |
Sequence modifications
B, E: 105 - 270 (UniProt: P49662)
| PDB | External Database | Details |
|---|---|---|
| Ala 258 | Cys 258 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 111753.3 | |
| All* | Total formula weight | 111753.3 |
