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22QU

Cryo-EM structure of the Deg-3/Des-2 betaine-bound open state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E
(A, B, C)
Acetylcholine receptor subunit alpha-type des-2polymer54862153.93UniProt (O76554)
Pfam (PF02931)
Pfam (PF02932)
Caenorhabditis elegans
2B, D
(D, E)
Acetylcholine receptor subunit alpha-type deg-3polymer56464997.02UniProt (P54244)
Pfam (PF02931)
Pfam (PF02932)
Caenorhabditis elegans
3F, M
(F, M)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.52In PDB
GlyTouCan (G15407YE)
4G, H, I, J, K...
(G, H, I, J, K...)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.46In PDB
GlyTouCan (G42666HT)
5N, Q, R, T, U
(A, D, B, E, C)
TRIMETHYL GLYCINEnon-polymer118.25Chemie (BET)
PubChem (248)
6O, P, S, V, W
(A, B, C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.25Chemie (NAG)
PubChem (24139)
7AA, BA, X, Y, Z
(E, C, A, D, B)
waterwater18.05Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight316455.5
BranchedNumber of molecules8
Total formula weight3719.5
Non-Polymers*Number of molecules10
Total formula weight1696.8
All*Total formula weight321871.8
*Water molecules are not included.

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PDB entries from 2026-08-19

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