22GK
C5a bound C5aR2 in complex with beta-arrestin1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | C5a anaphylatoxin | polymer | 74 | 8342.7 | 1 | UniProt (P01031) | Homo sapiens (human) | |
| 2 | B (R) | C5a anaphylatoxin chemotactic receptor 2 | polymer | 337 | 36513.2 | 1 | UniProt (Q9P296) | Homo sapiens (human) | Complement component 5a receptor 2,G-protein coupled receptor 77 |
| 3 | C (H) | Fab30 heavy chain | polymer | 229 | 24407.2 | 1 | Mus musculus | ||
| 4 | D (L) | Fab30 light chain | polymer | 215 | 23435.1 | 1 | Mus musculus | ||
| 5 | E (A) | Beta-arrestin-1 | polymer | 347 | 38980.8 | 1 | UniProt (P17870) | Bos taurus (domestic cattle) | Arrestin beta-1,Arrestin-2 |
Sequence modifications
C: 1 - 74 (UniProt: P01031)
A: 6 - 352 (UniProt: P17870)
| PDB | External Database | Details |
|---|---|---|
| Arg 27 | Cys 704 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Glu 169 | Arg 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 131679.0 | |
| All* | Total formula weight | 131679.0 |
