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22FF

Crystal structure of thioredoxin gluthathione reductase from Schistosoma japonicum with the U597C mutation in complex with auranofin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
thioredoxin-disulfide reductase (NADPH)polymer59865114.12Pfam (PF00462)
Pfam (PF07992)
Pfam (PF02852)
UniProt (by SIFTS) (A0A4Z2CZR5)
Schistosoma japonicum
2C, G
(A, B)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.52Chemie (FAD)
3D, E, F, H, I...
(A, B)
GOLD IONnon-polymer197.06Chemie (AU)
PubChem (114945)
4K, L
(A, B)
waterwater18.0416Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight130228.1
Non-Polymers*Number of molecules8
Total formula weight2752.9
All*Total formula weight132981.0
*Water molecules are not included.

254917

PDB entries from 2026-06-10

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