22AX
Cryo-EM structure of NSUN2-pre-tRNALeu-SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA cytosine C(5)-methyltransferase NSUN2 | polymer | 767 | 86557.7 | 1 | UniProt (Q08J23) | Homo sapiens (human) | Myc-induced SUN domain-containing protein,Misu,NOL1/NOP2/Sun domain family member 2,Substrate of AIM1/Aurora kinase B,mRNA cytosine C(5)-methyltransferase,tRNA cytosine C(5)-methyltransferase,tRNA methyltransferase 4 homolog,hTrm4 |
| 2 | B (B) | pre-tRNALeu | polymer | 110 | 35430.0 | 1 | Homo sapiens | ||
| 3 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) |
Sequence modifications
A: 1 - 767 (UniProt: Q08J23)
| PDB | External Database | Details |
|---|---|---|
| Ala 271 | Cys 271 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 121987.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 398.4 | |
| All* | Total formula weight | 122386.1 |
